Loop landmark to sprout vertical farm, research hub; Marc Calabria, Farm Zero eye 401 South State Street building as controlled agriculture campus

  • 2/12/2026

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Chicago Business Journal

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Highlights
The long-vacant eight-story landmark at 401 South State Street in Chicago's Loop is being proposed for redevelopment into an urban farming and food innovation hub.
Local investor Marc Calabria and vertical farming firm Farm Zero are partnering on the project to create a controlled-environment agriculture campus.
The plan includes vertical farming racks, research labs, a public market and a focus on "food as medicine" initiatives, alongside a potential conversion of a portion of the building to student or senior housing.

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